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Bioanalytical Research Associate - High Throughput Assay Development

Zero Acre Farms

Zero Acre Farms

San Mateo, CA, USA
Posted on Tuesday, November 15, 2022

Why We Exist

We believe a healthier world is possible with better oils and fats.

Vegetable oils account for 20% of our daily calories and have been linked to chronic disease, inflammation, obesity, and cognitive decline, as well as deforestation, biodiversity loss, and climate change, with no end in sight.

Vegetable oils are now the most consumed food in the world behind rice and wheat and are the fastest growing sub sector of global agriculture. More vegetable oil is consumed globally than all beef, chicken, cheese, and shrimp, combined.

The world needs an oil change.

Zero Acre Farms is on a mission to replace destructive vegetable oils in the food system with healthier, more sustainable oils and fats made by fermentation. Our first product, Cultured Oil, just launched DTC as we look ahead to retail, foodservice, and food manufacturing expansion.

Our Team

We’re a team of food lovers, nutrition believers, innovators, doctors, sustainability advocates, PhD’s, and problem solvers. We believe in taking care of our health and our planet’s health without sacrificing the foods we love. We started Zero Acre Farms out of concern for what we’re all involuntarily putting into our bodies and the profound effect it’s having on our health and the natural world.

Zero Acre Farms is backed by an incredible group of investors, including mission-driven VC’s, celebrities, influencers, and change makers.

The Role

Zero Acre Farms is seeking a Bioanalytical Research Associate – High Throughput Assay Development to join our growing Bioanalytical Team. The successful candidate will be highly motivated with a solid experience in analytical chemistry, quantitative analysis on HPLC, GC, LCMS, microtiter plate-based assay development, automation of the currently manual sample workup and execution using Tecan liquid handling robot and related automation tools. This position will work cross-functionally to understand, miniaturize, and run automated assays to support the rapid development of new production cultures and processes, and will directly contribute to Zero Acre mission to remove destructive vegetable oils from our food system.


  • Translate manual assays and sample preparation to automated liquid handling operation on Tecan handling robot. Assess, troubleshoot and analytically validate robotic steps for accuracy and precision. Carry out and maintain high throughput operations for small scale fermentation and sample processing for analytical measurements on GCMS and LCMS.
  • Edit scripts within Freedom EVOware software as necessary to improve quality and throughput.
  • Maintain laboratory automation instruments to support colony picking, liquid handling, plate management, and sample analysis, including Tecan Evo, Molecular Devices Qpix, Spectrophotometer plate reader, Agilent Bravo, Plate Sealer, Integra Viaflo.
  • Organize and support validation and QC of automated screening protocols.
  • Lead simplification and streamlining of HTP workflows with an eye for statistical precision, robustness, and time and material efficiencies.
  • Analyzed samples on HPLC, GC and LCMS
  • Collaborate with LIMS team to ensure robust sample tracking and data capture

You and Your Experience

  • BS or MS degree chemistry, analytical chemistry, biochemistry, bioengineering or equivalent with 2+ years of relevant industry experience
  • Experience with analytical chromatographic LC and GC separations, and quantitative analysis
  • Knowledge of Agilent GC, HPLC and LCMS instruments and software is a plus
  • Experience operating automated liquid handling systems
  • Proven ability to develop screening assays and optimize conditions to reduce variability
  • Strong data and statistics background applied to HTP screening
  • Experience with programming and management of a Tecan-Evo200 is a plus
  • Experience with sterile techniques, HTP fermentation, solvent handling, and HTP preparation of samples for a diversity of biochemical, spectroscopic, and analytical assays
  • Familiarity with LIMS environments and statistical software packages is a plus
  • Strong communication skills
  • Strong time management and organizational skills with a keen attention to detail
  • Thrive in a fluid, dynamic start-up environment building capabilities from the ground up

What We Offer

  • The excitement and purpose of a mission-driven startup and the stability of a well-funded company with experienced founders and executives at the helm
  • Empowered team members with minimal bureaucracy.
  • Competitive salary and meaningful equity.
  • Flexible vacation time (minimum 3 weeks).
  • Focus on uninterrupted deep work time.
  • Medical, dental, vision, long-term disability, life coverage, health and dependent care FSA (flexible spending account)
  • Additional perks like books and commuter assistance.

The following represents the expected range of compensation for this role: The estimated pay range for this role is $80-100,000. Additionally, this role is eligible to participate in Zero Acre Farms benefits and equity programs.

A Note From Our Founders

The majority of Americans are sick. Let that sink in. More people have a chronic disease than not in this country! 6 out of 10. And a hundred years ago, almost no one had a chronic disease. Our healthy life expectancy is decreasing for the first time in recorded history. Our solution so far has been more prescription drugs (in 2018, the average American filled eighteen prescriptions).

Our planet is also being destroyed by the day. The Amazon loses about 2 football fields of rainforest every minute, mostly to grow industrial monocrops like seed oils that make us sick. Species extinction is at an all time high. Some projections say we only have 60 harvests left before our soil doesn't support any more life.

The real issue? These problems are interconnected. We're destroying the planet to grow food that makes us sick.

How is this not one of the most important, urgent, and talked about issues of our generation? We want to change that. We want to slow down and ideally reverse the skyrocketing rates of chronic disease and environmental impact caused by what we eat. We truly believe that we can save millions of lives, as well as millions of acres of rainforest, if we are successful in our mission of replacing destructive vegetable oils in our food supply.

That’s what drives us, and we hope you’ll join us.